BIOINFORMATICS-II

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Introduction to genome, gene prediction in prokaryotes and eukaryotes, ORF, TFBS, codon usage table, EST and SNP databases, primer designing, restriction enzyme databases, RNA structure prediction, computational secondary and tertiary protein structure prediction methods, structure optimization and refinement methods, hydrogen bonding, PTMs of proteins, Chou Fasman, PHD and PSIPred, neural network, X-ray crystallography, NMR, ab initio, threading and homology modeling methods, protein fold identification using Pfam (A & B) and other tools.

Course Syllabus